Predictive value of childhood airway hyper‐responsiveness to indirect stimuli: 10‐year longitudinal study
نویسندگان
چکیده
منابع مشابه
Airway hyperresponsiveness and symptoms of asthma in a six-year follow-up study of childhood asthma.
BACKGROUND AND AIM In an inception cohort study of 457 asthmatic children diagnosed at the age of 3 to 4 years, airway hyperresponsiveness (AHR) was assessed 6 years after first diagnosis in a subgroup of 84 children. Our objective was to associate the level of AHR with the symptomatic asthma status at follow-up. METHODS Information on respiratory symptoms and medication use for the previous ...
متن کاملAre asymptomatic airway hyperresponsiveness and allergy risk factors for asthma? A longitudinal study.
Airway hyperresponsiveness (AHR) is a characteristic feature of asthma, but it is unclear whether asymptomatic AHR is associated with a higher risk of asthma. The present study assessed whether there is an association between asymptomatic AHR in adolescence and asthma in adulthood. The association between allergy and development of asthma was also investigated. A follow-up study of a general po...
متن کاملAre asymptomatic airway hyperresponsiveness and allergy risk factors for asthma? A longitudinal study
279–285. 9 Said SI, Rattan S. The multiple mediators of neurogenic smooth muscle relaxation. Trends Endocrinol Metab 2004; 15: 189–191. 10 Szema AM, Hamidi SA, Lyubsky S, et al. Mice lacking the VIP gene show airway hyperresponsiveness and airway inflammation, partially reversible by VIP. Am J Physiol Lung Cell Mol Physiol 2006; 291: L880–L886. 11 Hamidi SA, Prabhakar S, Said SI. Enhancement of...
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BACKGROUND Changes in airway mucosal osmolarity are an underlying mechanism of bronchoconstrictive responses to exercise and hypertonic saline (HS). The purpose of this study was to examine whether an osmotic challenge test using HS can predict exercise-induced bronchospasm (EIB) in asthma patients. METHODS Thirty-six young male asthmatic patients underwent bronchial challenge tests based on ...
متن کاملVirus-induced Airway Hyperresponsiveness
Intratracheal inoculation of parainfluenza type 3 virus to guinea pigs induces a marked increase in airway responsiveness in vivo and in vitro. In spontaneously breathing anesthetized guinea pigs inhalation of an aerosol containing the nitric oxide (NO) precursor L-argimine (2.0 mM) completely prevented the virus-induced airway hyperresponsiveness to histamine. In addition, perfusion of L-argin...
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ژورنال
عنوان ژورنال: Pediatric Allergy and Immunology
سال: 2020
ISSN: 0905-6157,1399-3038
DOI: 10.1111/pai.13248